background: preeclampsia is a disorder unique to pregnancy and has long been recognized as an important contributor of maternal and fetal morbidity and mortality. it is suggested that cytokines such as tumor necrosis factor-alpha (tnf-α) have an important role in the pathogenesis of preeclampsia and may cause generalized endothelial dysfunction. objective: the aim of this study was comparison o...

many species of tea (camellia sinensis) and cowslip (echium amoenum) are used in iranian traditional medicine. the aim of this study was to conduct the survey on the ability of iranian black tea and cowslip extracts on secretion of tumor necrosis factor-alpha (tnf-alpha) by non-infected and infected mouse macrophages. a macrophage infection model with legionella pneumophila and enzyme linked im...

crohn’s disease is an inflammatory bowel disease (ibd), characterized by chronic intestinal inflammation that causes the loss of immune tolerance leading to bizarre inflammatory signals and disruption of mucosal barriers. environmental triggers and interaction of genetic determinants also play an indispensible role. in this case report, we present a pre-pubertal girl with intermittent and refra...

conclusions the current study adds evidence to the association of tnf-α gene polymorphism and ms in this southern south iranian population which is consistent with the genetic analysis of ms in europeans (games) project reports and these two alleles reported in this study may be one of the genetic risk factor for ms. furthermore, this data can be used to build the iranian gene bank for future s...

background tnf-α is one of the most potent cytokines in proinflammatory reactions. results one hundred and twenty children with acute pyelonephritis were evaluated. urinary tnf-α/cr was 0.0051 ± 0.00083 pg/g creatinine. the authors found out a significant difference in urinary tnf-α/cr between patients who have normal and abnormal levels of urine leukocytes, urine protein, urine culture, erythr...

Background: Concentration of tumor necrosis factor alpha (TNF-alpha) might be useful in selecting patients with paroxysmal atrial fibrillation (PAF) who will benefit the most from pulmonary vein isolation.

results there was no difference found between the two groups with regard to; gender, basic variables, ejection fraction (ef), cbp time and aortic cross-clamp time. the preoperative levels of il-6 and tnf-α were not different; however, their postoperative levels were significantly higher in the placebo group (p value = 0.01 for il-6 and 0.005 for tnf-α). conclusions this study showed that mgso4 ...

conclusions taken together, pomegranate juice did not affect serum cytokines levels in patients with oa. its role in improving physical function in these patients most likely involves other mechanisms. background osteoarthritis (oa) is the most common musculoskeletal disorder causing disability and loss of function, particularly in the elderly. preclinical and in-vitro studies for mitigation of...